“Taurine made animals live healthier and longer lives by affecting all the major hallmarks of ageing.”īeyond improving health, mice on taurine lived longer – on average an extra 10% for males and 12% for females, amounting to an additional three to four months, the equivalent of seven or eight human years. “Whatever we checked, taurine-supplemented mice were healthier and appeared younger than the control mice,” Yadav said, noting they had denser bones, stronger muscles, better memory and younger looking immune systems. The discovery prompted the team to test the impact of extra taurine on middle-aged mice. By the age of 60, taurine levels in a typical person slumped to one-third of that seen in five-year-olds, they found.
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Yadav’s team homed in on taurine as a potential driver of the ageing process in 2012 when an analysis of blood compounds found that levels of the amino acid dropped dramatically with age in mice, monkeys and humans. “It will probably be very difficult to look at whether they live longer, but at least we can check if they live healthier for longer, and that of course is the goal for medicine.”
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Prof Henning Wackerhage, a molecular exercise physiologist on the team at the Technical University of Munich, said a trial would compare how humans fared after taking daily taurine or placebo supplements. “At the end of the day, these findings should be relevant to humans.” “This study suggests that taurine could be an elixir of life within us that helps us live longer and healthier lives.“Taurine abundance declines with age and reversal of this decline makes animals live longer and healthier lives,” said Dr Vijay Yadav, who led the research at Columbia University in New York. “For the last 25 years, scientists have been trying to find factors that not only let us live longer, but also increase healthspan, the time we remain healthy in our old age,” Yadav said.
The claims are frequent enough that Red Bull, which independently has a bovine name, addresses it on its list of frequently asked questions on its website. Such claims are not true and the chemical is produced synthetically. The nutrient’s bullish history also occasionally spark spurious claims that the drinks contain bull sperm or are made from bull’s testicles. Taurine is a common ingredient in many energy drinks-including best-selling brands like Red Bull, Monster and Rockstar-though experts warn these may pose a danger to public health for their large caffeine and sugar content. Its name is derived from the Latin word for bull or ox, “taurus,” as the chemical was first isolated from ox bile in the early 1800s. Taurine is a naturally occurring amino acid. Yadav said the finding “suggests that some of the health benefits of exercise may come from an increase in taurine.” Surprising Fact The researchers tested taurine levels in men-a mix of athletes and less-active individuals-after a strenuous workout, finding a significant increase for all. The researchers also conducted a study linking taurine levels with exercise, another intervention well-known to improve health. Rigorous and randomized clinical trials will be needed to prove the link for sure, Yadav said. As the study was observational, Yadav said it can’t prove taurine was responsible for the findings or whether supplements would help improve lifespan and health. To test the connection, the researchers evaluated 12,000 European adults ages 60 and over on around 50 health metrics, finding those with higher taurine levels to be healthier, with fewer cases of type 2 diabetes, reduced high blood pressure and lower levels of obesity and inflammation.
The role taurine may play in human aging is not yet clear and understanding it fully will still leave many questions unresolved.
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While important strides have been made in recent years, there is still a great deal scientists do not know about aging, its drivers or how to slow, stall or reverse it. Similar health effects of taurine supplementation were also seen in middle-aged rhesus monkeys, the researchers said, where six months of daily supplements prevented weight gain, increased bone density in the spine and legs and improved immune system health.
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